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Cutting edge: developmental up-regulation of IFN-gamma-inducible lysosomal thiol reductase expression leads to reduced T Cell Sensitivity and less severe autoimmunity. J Immunol. 2009 Jan 15;182(2):746-50 Authors: Maric M, Barjaktarevic I, Bogunovic B, Stojakovic M, Maric C, Vukmanovic S Reactivity
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Lysosomal cysteine peptidase cathepsin l protects against cardiac hypertrophy through blocking akt/gsk3β signaling
Abstract  The lysosomal cysteine peptidase cathepsin L (CTSL) is an important lysosomal proteinase involved in a variety of cellular functions including intracellular protein turnover, epidermal homeostasis, and hair development. Deficiency of CTSL in mice results in a progressive dilated cardiomyopathy. In the present study, we tested the hypothesis that
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California Senate President Aims To Pass Plan To Cover All Children Within First 120 Days Of New Session
California Senate President Pro Tempore Darrell Steinberg (D) said providing health coverage to all California children will be one of the issues he addresses within the first 120 days of the new legislative session, the Sacramento Bee reports. About 800,000 California children are uninsured. More: continued
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Cxcr4 receptor antagonist blocks cardiac myocyte p38 map kinase phosphorylation by hiv gp120.
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Somalia: Surge In Wounded And Displaced As Violence Increases In Mogadishu
The recent escalation in fighting in one of Mogadishu’s most populated residential areas has resulted in a surge of wounded civilians and has once again displaced thousands of people. The international medical humanitarian organization Doctors Without Borders/Médecins Sans Frontières (MSF) is treating some of the wounded and
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