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[Original articles] Wild-type but not mutant huntingtin modulates the transcriptional activity of liver X receptors
Conclusion: Our data suggest a novel function for wild-type huntingtin as a co-factor of LXR. However, this activity is lost by mutant huntingtin that only interacts weakly with LXR. (Source: Journal of Medical Genetics)
[Original articles] Wild-type but not mutant huntingtin modulates the transcriptional activity of liver X receptors...

Structural elucidation of metabolites of ginkgolic acid in rat liver microsomes by ultra-performance liquid chromatography/electrospray ionization tandem mass spectrometry and hydrogen/deuterium exchange.
This study might be useful for the investigation of toxicological mechanism of ginkgolic acids. PMID: 19462408 [PubMed - in process] (Source: Rapid Communications in Mass Spectrometry : RCM)
Structural elucidation of metabolites of ginkgolic acid in rat liver microsomes by ultra-performance liquid chromatography/electrospray ionization tandem mass spectrometry and hydrogen/deuterium exchange....

Mantle Cell Lymphoma Consortium Scientific Workshop - Report From Sixth Annual Meeting Now Available
Almost 60 mantle cell lymphoma (MCL) specialists from around the world gathered in Atlanta, GA for the Lymphoma Research Foundation’s (LRF) Sixth Annual Mantle Cell Lymphoma Consortium (MCLC) Scientific Workshop. Attendees heard presentations addressing several key issues including the biology of MCL, prognostic indicators, new molecular
Mantle Cell Lymphoma Consortium Scientific Workshop - Report From Sixth Annual Meeting Now Available...

Ontario Women Live Longer Than Men But Don't Prosper
While Ontario women live longer than men, a majority are more likely to suffer from disability and chronic conditions, according to a new women's health study. What's more, low-income women have more chronic conditions, greater disability and a shorter life expectancy than women in high-income groups.
Ontario Women Live Longer Than Men But Don't Prosper...

Multiple Myeloma Research Consortium (MMRC) Activates Clinical Trials 30-40 Percent Faster Than Industry Standard
The Multiple Myeloma Research Consortium (MMRC), an innovative research model comprised of a network of 15 academic Member Institutions across North America and leadership in Norwalk, Connecticut, announced preliminary data from an analysis showing that clinical trials opened through its clinical trials network were activated 30 to 40
Multiple Myeloma Research Consortium (MMRC) Activates Clinical Trials 30-40 Percent Faster Than Industry Standard...

Sirolimus Use in Stable Liver Transplant Patients May Increase Mortality
FDA today issued an alert notifying health care professionals of data suggesting increased mortality in stable liver transplant recipients whose maintenance therapy with a calcineurin inhibitor has been changed to sirolimus.
Sirolimus Use in Stable Liver Transplant Patients May Increase Mortality...

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