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Recent related articles ( Twentieth century fox):

[Short reports] Functional evidence implicating FOXL2 in non-syndromic premature ovarian failure and in the regulation of the transcription factor OSR2
Conclusions: Our data provide evidence in favour of the implication of FOXL2 variants in non-syndromic POF and confirm the regulatory interaction between FOXL2 and OSR2 whose perturbation might contribute to the palpebral abnormalities observed in BPES patients. (Source: Journal of Medical Genetics)
[Short reports] Functional evidence implicating FOXL2 in non-syndromic premature ovarian failure and in the regulation of the transcription factor OSR2...

CD4+CD25highFoxp3+ regulatory T cells downregulate human V2+ T-lymphocyte function triggered by anti-CD3 or phosphoantigen

CD4+CD25highFoxp3+ regulatory T cells downregulate human V2+ T-lymphocyte function triggered by anti-CD3 or phosphoantigen...

FOXP3 expression following bone marrow transplantation for IPEX syndrome after reduced-intensity conditioning
The objective of this study is to determine if immune reconstitution of FOXP3+ T regulatory cells correlates with clinical improvement of IPEX syndrome following allogeneic hematopoietic stem cell transplant. An 8-months-old male infant with a mutation in the polyadenylation site of FOXP3 gene, absence of FOXP3 protein expression
FOXP3 expression following bone marrow transplantation for IPEX syndrome after reduced-intensity conditioning...

Protein geranylgeranylation regulates the balance between Th17 cells and Foxp3+ regulatory T cells
Recent studies have suggested that statins, the inhibitors for 3-hydroxy-3-methyglutaryl (HMG)-CoA reductase in the mevalonate pathway, exhibit anti-inflammatory effects. However, the immune modulatory effects of statins on the differentiation of CD4+ T cells and their underlying mechanisms are still largely unknown. To address these issues, we examined the
Protein geranylgeranylation regulates the balance between Th17 cells and Foxp3+ regulatory T cells...

Altered homeostasis of CD4+FoxP3+ regulatory T-cell subpopulations in systemic lupus erythematosus
(Source: Immunology) MedWorm Message: Get the very latest Swine Flu news via the MedWorm Swine Flu RSS news feed - updated hourly from thousands of authoritative health and news sources.
Altered homeostasis of CD4+FoxP3+ regulatory T-cell subpopulations in systemic lupus erythematosus...

Dendritic cells as controllers of antigen-specific Foxp3+ regulatory T cells
Abstract: Regulatory T cells (Treg) are a subpopulation of CD4+ lymphocytes that maintain immunological self-tolerance in the periphery. Treg also regulate or suppress other classes of immune response such as allograft rejection, allergy, tumor immunity, and responses to microbes. Treg express the Foxp3 transcription factor and CD25, the
Dendritic cells as controllers of antigen-specific Foxp3+ regulatory T cells...

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