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Invited review: deterioration of the immune system after trauma: signals and cellular mechanisms.
Invited review: Deterioration of the immune system after trauma: signals and cellular mechanisms. Innate Immun. 2008 Dec;14(6):333-44 Authors: Flohé SB, Flohé S, Schade FU Multiple trauma leads to a deterioration of the immune system. On the one hand, hyperinflammation
Invited review: deterioration of the immune system after trauma: signals and cellular mechanisms....

Cutting edge: selective blockade of light-lymphotoxin {beta} receptor signaling protects mice from experimental cerebral malaria caused by plasmodium berghei anka.
In this study we report a role for LIGHT-lymphotoxin beta Receptor (LTbetaR) signaling in the development of ECM and control of parasite growth. Specific blockade of LIGHT-LTbetaR, but not LIGHT-herpesvirus entry mediator interactions, abrogated the accumulation of parasites and the recruitment of pathogenic CD8(+) T cells and monocytes
Cutting edge: selective blockade of light-lymphotoxin {beta} receptor signaling protects mice from experimental cerebral malaria caused by plasmodium berghei anka....

Nervous about immunity: neuronal signals control innate immune system
Authors: Cheng-Yuan Kao, Ferdinand C O Los & Raffi V Aroian The molecular mechanisms by which the nervous system influences innate immunity to pathogens remain mysterious. Two new studies show that neuronal products modulate established innate immune signaling pathways operative in the Caenorhabditis elegans intestine. (Source: Nature Immunology) MedWorm Sponsored Message:
Nervous about immunity: neuronal signals control innate immune system...

The effect of β-blocker on hamster model bio 53.58 with dilated cardiomyopathy determined using123i-mibg myocardial scintigraphy
Conclusions: The delayed image H/M and WR acutely reflected cardiac disorder and sympathetic nerve function disorder in BIO 53.58 hamsters. In the carvedilol-administered groups, there was improvement compared to the initial H/M image, indicating the efficacy of the β-blocker in DCM. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/BF02984974Authors Aritomo
The effect of β-blocker on hamster model bio 53.58 with dilated cardiomyopathy determined using123i-mibg myocardial scintigraphy...

Risk of angioedema with angiotensin receptor blockers in patients with prior angioedema associated with angiotensin-converting enzyme inhibitors: a meta-analysis

Risk of angioedema with angiotensin receptor blockers in patients with prior angioedema associated with angiotensin-converting enzyme inhibitors: a meta-analysis...

[mechanisms of signal transduction] dusp6 (mkp3) null mice show enhanced erk1/2 phosphorylation at baseline and increased myocyte proliferation in the heart affecting disease susceptibility
The strength and duration of mitogen-activated protein kinase signaling is regulated through phosphorylation and dephosphorylation by dedicated dual-specificity kinases and phosphatases, respectively. Here we investigated the physiological role that extracellular signal-regulated kinases 1/2 (ERK1/2) dephosphorylation plays in vivo through targeted disruption of the gene encoding dual-specificity phosphatase 6
[mechanisms of signal transduction] dusp6 (mkp3) null mice show enhanced erk1/2 phosphorylation at baseline and increased myocyte proliferation in the heart affecting disease susceptibility...

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