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Recent related articles ( choline an alternative therapy for asthma):

The relationship of inflammatory cytokines with asthma and obesity.
Conclusion: We identified a relationship between acute phase reactants and inflammatory cytokines, and the criteria for obesity in obese asthma patients. Inflammation markers were at their highest levels in obese asthma patients. Leptin levels were considerably higher in obese patients than in normal weight controls. Like obesity, leptin
The relationship of inflammatory cytokines with asthma and obesity....

Innate immunity in asthma.
Authors: Simpson JL, Brooks C, Douwes J Asthma is a complex disorder and evidence now suggests that it is not solely attributable either to allergy or eosinophilia. Non-eosinophilic asthma accounts for up to one half of all cases and a large proportion have a non-allergic
Innate immunity in asthma....

Immunotherapy: designer sirna
Immunotherapy: Designer siRNA Nature Reviews Immunology 8, 906 (2008). doi:10.1038/nri2465 Author: Lucy Bird RNA interference — a process by which short RNA oligonucleotides silence the expression of specific target genes — has received much attention as a potential approach for the treatment of numerous diseases, including cancer. However, the specificity of
Immunotherapy: designer sirna...

Immunotherapy of autoimmunity and cancer: the penalty for success
Nature Reviews Immunology 8, 970 (2008). doi:10.1038/nri2438 Author: Rachel R. Caspi Advances in our understanding of autoimmunity and tumour immunity have led to improvements in immunotherapy for these diseases. Ironically, effective tumour immunity requires the induction of the same responses that underlie autoimmunity, whereas autoimmunity is driven by dysregulation of
Immunotherapy of autoimmunity and cancer: the penalty for success...

Original investigation: comparison of cardiovascular outcomes in elderly patients with diabetes who initiated rosiglitazone vs pioglitazone therapy
Conclusions  Our findings from a large population-based cohort of US seniors are compatible with an increased risk of all-cause mortality and congestive heart failure in patients initiating therapy with rosiglitazone compared with similar patients initiating therapy with pioglitazone. Limitations of this study include residual confounding due to its
Original investigation: comparison of cardiovascular outcomes in elderly patients with diabetes who initiated rosiglitazone vs pioglitazone therapy...

Proinsulin peptide immunotherapy in type 1 diabetes: report of a first-in-man phase i safety study
This study evaluated safety and mechanistic outcomes during first-in-man intradermal administration of a human leucocyte antigen-DR4 (HLA-DR4)-restricted peptide epitope of proinsulin (C19-A3). This randomized, open-label study assessed two major theoretical risks of peptide immunotherapy, namely induction of allergic hypersensitivity and exacerbation of the proinflammatory autoimmune response, using clinical
Proinsulin peptide immunotherapy in type 1 diabetes: report of a first-in-man phase i safety study...

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