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Recent related articles ( flick of the switch):

Switches of Antiepileptic Drug Products Come Under Fire
A patient advocacy group’s campaign and the media’s recent focus on generic drug substitution have increased the need for pharmacists to judge FDA-declared bioequivalent products by more than just price, say two pharmacists who work at epilepsy clinics.
Switches of Antiepileptic Drug Products Come Under Fire...

The CD160, BTLA, LIGHTHVEM pathway: a bidirectional switch regulating T-cell activation

The CD160, BTLA, LIGHTHVEM pathway: a bidirectional switch regulating T-cell activation...

Comment on "Reassessment of the role of mut S homolog 5 in Ig class switch recombination shows lack of involvement in cis- and trans-switching".
Authors: Sekine H, Ferreira RC, Pan-Hammarström Q, Hammarström L, Gilkeson GS, Behrens TW PMID: 19342619 [PubMed - in process] (Source: Journal of Immunology) MedWorm Message: Find out how you can get your message across here by sponsoring this MedWorm news feed.
Comment on "Reassessment of the role of mut S homolog 5 in Ig class switch recombination shows lack of involvement in cis- and trans-switching"....

Chapter 5 DNA Targets of AID Evolutionary Link Between Antibody Somatic Hypermutation and Class Switch Recombination.
We describe properties of the S sequences, and discuss species and isotypic differences among S regions. Common properties of SHM and CSR target sequences suggest that evolution of S regions might involve the duplication and selection of SHM hotspots. PMID: 19231595 [PubMed - in process]
Chapter 5 DNA Targets of AID Evolutionary Link Between Antibody Somatic Hypermutation and Class Switch Recombination....

Determining How ‘Gene Switch’ Works: Using Tuberculosis Bacteria To End 25-Year Quest
The bacterium behind one of mankind’s deadliest scourges, tuberculosis, is helping researchers at the Commerce Department’s National Institute of Standards and Technology (NIST) and the Department of Energy’s Brookhaven National Laboratory (BNL) move closer to answering the decades-old question of what controls the switching on and off of
Determining How ‘Gene Switch’ Works: Using Tuberculosis Bacteria To End 25-Year Quest...

Arc is a critical cardiomyocyte survival switch in doxorubicin cardiotoxicity
In this study, we provide evidence for the protective role of anti-apoptotic ARC in Dox-induced cardiotoxicity, which makes this molecule an interesting target for future therapies. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00109-008-0434-zAuthors Junfeng An, Max-Delbrück-Center for Molecular Medicine Department of Cardiology, Charité Campus Buch, Experimental Clinical Research
Arc is a critical cardiomyocyte survival switch in doxorubicin cardiotoxicity...

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