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Recent related articles ( gsk accused monopolizing wellbutrin fiercepharma):

Lysosomal cysteine peptidase cathepsin l protects against cardiac hypertrophy through blocking akt/gsk3β signaling
Abstract  The lysosomal cysteine peptidase cathepsin L (CTSL) is an important lysosomal proteinase involved in a variety of cellular functions including intracellular protein turnover, epidermal homeostasis, and hair development. Deficiency of CTSL in mice results in a progressive dilated cardiomyopathy. In the present study, we tested the hypothesis that
Lysosomal cysteine peptidase cathepsin l protects against cardiac hypertrophy through blocking akt/gsk3β signaling...

Ifn-beta production by tlr4-stimulated innate immune cells is negatively regulated by gsk3-beta.
In this study, we demonstrate glycogen synthase kinase 3-beta (GSK3-beta) plays a fundamental role in this process. Suppression of GSK3-beta activity by either pharmacological inhibition, small interfering RNA-mediated gene silencing, or ectopic expression of a kinase-dead GSK3-beta mutant enhanced IFN-beta production by TLR4-stimulated macrophages. Conversely, ectopic expression of
Ifn-beta production by tlr4-stimulated innate immune cells is negatively regulated by gsk3-beta....

Deletion of gsk-3{beta} in mice leads to hypertrophic cardiomyopathy secondary to cardiomyoblast hyperproliferation
We report that terminal cardiomyocyte differentiation was substantially blunted in Gsk3b–/– embryoid bodies. While GSK-3α–deficient mice were born without a cardiac phenotype, no live-born Gsk3b–/– pups were recovered. The Gsk3b–/– embryos had a double outlet RV, ventricular septal defects, and hypertrophic myopathy, with near obliteration of the ventricular
Deletion of gsk-3{beta} in mice leads to hypertrophic cardiomyopathy secondary to cardiomyoblast hyperproliferation...

Cellini accused of shaking down firm
A federal grand jury Thursday indicted Bill Cellini, a longtime Springfield-area political fundraiser and a key player in Sangamon County and state politics for decades, on charges of conspiracy and extortion.
Cellini accused of shaking down firm ...

GSK Receives Positive Opinion For Alli(R) (orlistat 60 Mg) As A Non-prescription Weight Loss Aid In Europe
Thursday 23 October 2008, London GlaxoSmithKline (GSK) announced today that alli (orlistat 60 mg) has received a positive opinion as a non-prescription product from the Committee for Medicinal Products for Human Use (CHMP). This means the product will now be proposed for final approval by the European
GSK Receives Positive Opinion For Alli(R) (orlistat 60 Mg) As A Non-prescription Weight Loss Aid In Europe...

Lawyer accused of bilking Texas with shoddy filings - Austin American-Statesman (subscription)

Lawyer accused of bilking Texas with shoddy filings
Austin American-Statesman (subscription), TX - Sep 27, 2007
... prominently in the American-Statesman examination of the state habeas system, was a collection of first-person rants, misspellings and bad grammar. ...

Lawyer accused of bilking Texas with shoddy filings - Austin American-Statesman (subscription)...

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