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Recent related articles ( move to the city live):

[Original articles] Wild-type but not mutant huntingtin modulates the transcriptional activity of liver X receptors
Conclusion: Our data suggest a novel function for wild-type huntingtin as a co-factor of LXR. However, this activity is lost by mutant huntingtin that only interacts weakly with LXR. (Source: Journal of Medical Genetics)
[Original articles] Wild-type but not mutant huntingtin modulates the transcriptional activity of liver X receptors...

NYC: Aiming Wide in City War on Smoking
The city wants to require shops that sell cigarettes to post health notices that will include a photo of blackened lungs.


NYC: Aiming Wide in City War on Smoking...

Structural elucidation of metabolites of ginkgolic acid in rat liver microsomes by ultra-performance liquid chromatography/electrospray ionization tandem mass spectrometry and hydrogen/deuterium exchange.
This study might be useful for the investigation of toxicological mechanism of ginkgolic acids. PMID: 19462408 [PubMed - in process] (Source: Rapid Communications in Mass Spectrometry : RCM)
Structural elucidation of metabolites of ginkgolic acid in rat liver microsomes by ultra-performance liquid chromatography/electrospray ionization tandem mass spectrometry and hydrogen/deuterium exchange....

New developments in anthracycline-induced cardiotoxicity.
Authors: Mordente A, Meucci E, Silvestrini A, Martorana GE, Giardina B Anthracyclines are among the most effective anticancer drugs ever developed. Unfortunately, their clinical use is severely limited by the development of a progressive dose-dependent cardiomyopathy that irreversibly evolves toward congestive heart failure, usually refractory
New developments in anthracycline-induced cardiotoxicity....

Ontario Women Live Longer Than Men But Don't Prosper
While Ontario women live longer than men, a majority are more likely to suffer from disability and chronic conditions, according to a new women's health study. What's more, low-income women have more chronic conditions, greater disability and a shorter life expectancy than women in high-income groups.
Ontario Women Live Longer Than Men But Don't Prosper...

Capacity of purified peanut allergens to induce degranulation in a functional in vitro assay: Ara h 2 and Ara h 6 are the most efficient elicitors
Peanut is a most common and potent food allergen. Many peanut allergens have been characterized using, in particular, IgE-binding studies. We optimized an in vitro functional assay to assess the capacity of peanut allergens to degranulate humanized rat basophilic leukaemia cells, RBL SX-38 cells, after sensitization by serum
Capacity of purified peanut allergens to induce degranulation in a functional in vitro assay: Ara h 2 and Ara h 6 are the most efficient elicitors...

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