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Total Swine Flu A(H1N1) Human Infection Cases Reach 7,447 In The United Kingdom
The Health Protection Agency (HPA), UK, informed yesterday 3rd July, 2009, in its weekly update that the total number of confirmed human cases of Swine Flu A(H1N1) infection has reached 7,447. British health authorities estimate that the figure will be over 100,000 by the end of this summer.
Total Swine Flu A(H1N1) Human Infection Cases Reach 7,447 In The United Kingdom...

Prognostic value of the collagen volume fraction in hypertrophic cardiomyopathy
FUNDAMENTO: Na cardiomiopatia hipertrófica (CMH), a fibrose miocárdica intersticial é uma importante alteração histológica que tem sido associada com morte súbita e evolução para dilatação. OBJETIVO: Avaliar, prospectivamente, o valor prognóstico da fração de colágeno na CMH. MÉTODOS:Biópsia endomiocárdica do ventrículo direito foi realizada com sucesso em 21
Prognostic value of the collagen volume fraction in hypertrophic cardiomyopathy...

ASMase: the tailor of cytotoxic T cell granule exocytosis
ASMase: the tailor of cytotoxic T cell granule exocytosis Nature Immunology 10, 683 (2009). doi:10.1038/ni0709-683 Author: Christian Bogdan Deficiency in acid sphingomyelinase causes lysosomal storage of sphingomyelin, mediates resistance to stress-induced apoptosis and alters susceptibility to certain infections. New work links acid sphingomyelinase to the granule exocytosis of cytotoxic T
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Interleukin-4 suppresses the cytotoxic potential of in vitro generated, adaptive regulatory CD4+ T cells by down-regulation of granzyme B

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Contents (Volume 80)

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Loss of the pro-apoptotic BH3-only Bcl-2 family member Bim sustains B lymphopoiesis in the absence of IL-7
IL-7 is pivotal for B cell development. Proteins of the Bcl-2 family are essential regulators of lymphocyte survival. Particularly, the pro-apoptotic BH3-only members Bim and Puma mediate lymphocyte apoptosis provoked by cytokine deprivation. Herein, we addressed whether the absence of Bim or Puma within the hematopoietic compartment could
Loss of the pro-apoptotic BH3-only Bcl-2 family member Bim sustains B lymphopoiesis in the absence of IL-7...

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