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Current understanding and management of dilated cardiomyopathy in Duchenne and Becker muscular dystrophy
Conclusions: Duchenne and Becker muscular dystrophies are debilitating neuromuscular disorders, both caused by mutations in the dystrophin gene. Most patients develop DCM as part of the disease course; in fact, DCM is the leading cause of death among these patients. Cardiac surveillance, including routine monitoring of electrocardiograms,
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Understanding A Target Of Quinoline Drugs
The full details about the molecules and mechanisms that underlie the development of autoimmune diseases, such as multiple sclerosis and systemic lupus erythematosus, remain to be discovered. One compound that may have a role in alleviating these conditions is quinoline-3-carboxamide. Researchers have now identified a molecular target for
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New Understanding of Dengue Virus Points Way to Possible Therapies for Dengue Fever
Source: National Institute of Allergy and Infectious Diseases (Source: MedlinePlus Health News)
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Towards an understanding of the adjuvant action of aluminium
Authors: Philippa Marrack, Amy S. McKee & Michael W. Munks The efficacy of vaccines depends on the presence of an adjuvant in conjunction with the antigen. Of these adjuvants, the ones that contain aluminium, which were first discovered empirically in 1926, are currently the most widely used. However, a detailed
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Philip Morris’s Support Casts Shadow Over a Bill to Limit Tobacco
The legislation, which authorizes the F.D.A. to approve or reject tobacco products and ingredients, is expected to be approved by the House, but could meet resistance in the Senate.
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The understanding of hypertrophic cardiomyopathy (HCM) has changed dramatically over the last few decades, and it is now understood to be caused by a mutation in one of several cardiac sarcomeric genes. Due to complications such as outflow tract obstruction, diastolic dysfunction, arrhythmias, stroke, infective endocarditis and sudden
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