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Proinsulin peptide immunotherapy in type 1 diabetes: report of a first-in-man phase i safety study
This study evaluated safety and mechanistic outcomes during first-in-man intradermal administration of a human leucocyte antigen-DR4 (HLA-DR4)-restricted peptide epitope of proinsulin (C19-A3). This randomized, open-label study assessed two major theoretical risks of peptide immunotherapy, namely induction of allergic hypersensitivity and exacerbation of the proinflammatory autoimmune response, using clinical
Proinsulin peptide immunotherapy in type 1 diabetes: report of a first-in-man phase i safety study...

Acaai 2008: intranasal steroid outperforms antihistamine in relieving nighttime allergy symptoms
A direct comparison of fluticasone furoate nasal spray and oral fexofenadine showed that fluticasone better relieves nighttime symptoms of seasonal allergic rhinitis. Medscape Medical News (Source: Medscape Medical News Headlines)
Acaai 2008: intranasal steroid outperforms antihistamine in relieving nighttime allergy symptoms...

Sumoylation of peroxisome proliferator-activated receptor gamma by apoptotic cells prevents lipopolysaccharide-induced ncor removal from kappab binding sites mediating transrepression of proinflammatory cytokines.
Related Articles Sumoylation of peroxisome proliferator-activated receptor gamma by apoptotic cells prevents lipopolysaccharide-induced NCoR removal from kappaB binding sites mediating transrepression of proinflammatory cytokines. J Immunol. 2008 Oct 15;181(8):5646-52
Sumoylation of peroxisome proliferator-activated receptor gamma by apoptotic cells prevents lipopolysaccharide-induced ncor removal from kappab binding sites mediating transrepression of proinflammatory cytokines....

Differential pathways govern cd4+ cd28- t cell proinflammatory and effector responses in patients with coronary artery disease.
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Differential pathways govern cd4+ cd28- t cell proinflammatory and effector responses in patients with coronary artery disease....

Patient-controlled nasal steroids quell rhinitis with less drug
SONGKHLA, Thailand (MedPage Today) -- Allergic rhinitis patients self-titrating inhaled steroids doses by their own needs can achieve near-maximal symptom control with less drug, investigators here reported. (Source: MedPage Today Allergy)
Patient-controlled nasal steroids quell rhinitis with less drug...

Obesity linked to reduced steroid response in asthmatics
The cellular response to dexamethasone is reduced in overweight/obese patients with asthma relative to their lean counterparts, according to a report in the first October issue of the American Journal of Respiratory and Critical Care Medicine. Reuters Health Information (Source: Medscape Allergy Headlines)
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